2017 International Symposium on Pheochromocytoma and Paraganglioma Videos

Symposium 1: Overview of Progress since ISP 2014

The TCGA data on phaeochromocytoma and paraganglioma

Presenter: Dr. Lauren Fishbein

Neuropilins guide preganglionic sympathetic axons to establish the adrenal medulla

Presenter: Dr. Quenten Schwarz

What do patients expect from us?

Presenter: Simone Leyden, Unicorn Foundation

Symposium 2: Pathology and pre-clinical models

Beyond Paragangliomas: Getting the GIST of Syndromically Associated Tumors

Presenter: Dr. Arthur S. Tischler

Succinate dehydrogenase (SDH) deficient neoplasia

Presenter: Dr. Anthony Gill

Role of microenvironment in Pheochromocytoma/Paraganglioma growth and invasiveness

Presenter: Dr. Massimo Mannelli

Characterization of cultured multipotent human fetal neural crest-derived cells

Presenter: Dr. Elena Rapizzi

Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a normetanephrine dominant phenotype

Presenter: Dr. Peter MT Deen

Synthetic lethal testing in a mouse embryonic fibroblast model of SDH-loss human familial paraganglioma

Presenter: Dr. Oksana Hamidi

Symposium 3: Biochemical Diagnostics and Imaging

The biological basis for PET imaging in PCC/PGL

Presenter: Dr. Rodney Hicks

Role of 68-Gallium Dotatate-PET/CT in pre-operative assessment of phaeochromocytoma and paraganglioma Impact of 123 I-MIBG scintigraphy on clinical decision making in patients with pheochromocytoma and paraganglioma   

Presenter: Dr. Matti Gild



Symposium 4: Genetics I

Novel and less well-known cluster 2-related PPGLs

Presenter: Dr. Patricia Dahia

Lessons From MTC Applicable To Pheochromocytoma

Presenter: Dr. Bruce Robinson

A Bayesian approach to determining penetrance of pathogenic variants in genes for hereditary pheochromocytoma/paraganglioma syndromes

Presenter: Dr. Roderick Clifton-Bligh

Symposium 5: Genetics II and Metabolism

Mitochondrial defects in cancer

Presenter: Dr. Rae-Anne Hardie

Investigating the metabolism of SDH-mutated disease for novel target identification

Presenter: Dr. Daniel Tennant

PRESSOR Young Investigator Award Session – William Manger Award

In vivo detection of succinate by magnetic resonance spectroscopy as a hallmark of SDHx mutations in paraganglioma

Presenter: Dr. Charlotte Lussey-Lepoutre

Succinate mediated autocrine tumorigenic effects in succinate dehydrogenase deficient paragangliomas: Potential for new-targeted treatment strategies

Presenter: Dr. Stephanie MJ Fliedner

Optimized procedures for diagnostic testing for pheochromocytomas/paragangliomas in patients with chronic kidney disease

Presenter: Dr. Christina Pamporaki

Symposium 6: Genetics III

From integrative OMICS studies to precision medicine in PPGLs

Presenter: Dr. Anne-Paule Gimenez-Roqueplo

New genetic loci for malignant PPGLs

Presenter: Dr. Mercedes Robledo

Pheo-type: molecular subclassification of pheochromocytoma

Presenter: Dr. Richard Tothill

Structural rearrangements involving the TERT promoter region identified in metastatic pheochromocytomas

Presenter: Dr. Trish Dwight

Targeted exome sequencing of Krebs cycle genes reveals candidate cancer predisposing mutations in pheochromocytomas and paragangliomas

Presenter: Dr. Alberto Cascon Soriano

Symposium 7: Management I - New Horizons

Clinical Trials for Patients with Malignant Pheochromocytomas and Paragangliomas: What Have We Learned? Where Are We Going?

Presenter: Dr. Camilo Jimenez

Immunotherapies: a turning point for cancer treatment

Presenter: Dr. Paul Neeson

AZEDRA® (iobenguane I 131) in patients with malignant and/or recurrent pheochromocytoma/paraganglioma (PPGL):  final results of a multi-center, open-label, pivotal phase 2b study

Presenter: Dr. Daniel A. Pryma

Ask-the-Expert Session

A storybook to help young children understand being at risk for hereditary PPGL

Presenter: Georgina Schlub

Symposium 8: Case Presentations - Why we make the decisions we do

Use of somatostatin analog therapy in patients with advanced pheochromocytoma/paraganglioma and somatostatin-receptor avid disease

Presenter: Dr. Debbie Cohen

Cardiac paraganglioma in siblings with SDHB mutation: Evidence for a genetic or environmental modifier?

Presenter: Dr. Amanda J. Love

A case of malignant paraganglioma of urinary bladder with metastatic lesions in the bone, lung, pleura, lymph node, and esophagus

Presenter: Dr. Tatsuki Ogasawara

Symposium 9: Management II


Presenter: Dr. Rod Hicks

A Phase 2 Study to Evaluate the Effects of Cabozantinib in Patients with unresectable Metastatic Pheochromocytomas and Paragangliomas

Presenter: Dr. Camilo Jimenez

Symposium 10: Paediatric PPGLS

Genetic approach to paediatric diagnosis

Presenter: Dr. Roderick Clifton-Bligh

Phenotype and penetrance of germline SDHA mutations in 30 Dutch families

Presenter: Dr. FJ Hes

Systematic in vitro study of germline EPAS1 variants associated with phaeochromocytoma and paraganglioma

Presenter: Dr. Edward Kim